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Tanezumab (CAT#: TAB-111)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Anti-Human NGF Recombinant Antibody TAB-111 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to NGF. Tanezumab (INN, codenamed RN624) is a monoclonal antibody against nerve growth factor, as a treatment for pain.
  • Target
  • NGF
  • Type
  • IgG2
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
  • CAS
  • 880266-57-9
  • Specific Activity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G2, anti-(human nerve growth factor) humanized mouse monoclonal RN624 (Lys71,Ser330,Ser331)gamma2 heavy chain (135-214")-disulfide with kappa light chain (223-223"":224-224"":227-227"":230-230"")-tetrakisdisulfide dimer
  • Predicted N terminal
  • H chain: QVQLQES; L chain: DIQMTQS
  • Molecular Weight
  • 145400
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons.
  • Function
  • growth factor activity; nerve growth factor receptor binding; receptor signaling protein activity;
  • Synonyms
  • NGF; nerve growth factor (beta polypeptide); NGFB; beta-nerve growth factor; nerve growth factor, beta subunit; HSAN5; Beta-NGF; MGC161426; MGC161428;

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